Genome Stability and Evolution
Fumiko Esashi
Investigating the mechanisms that drive changes in the genome during cell growth and dormancy
Molecular Mechanisms of RNA Virus Replication
Ervin Fodor
Elucidating the fundamental mechanisms underlying the replication of RNA viruses such as Influenza, Nipah, and SARS-CoV-2
Cell Biology of Signalling
Matthew Freeman
Investigating the interface between membrane proteins, the cell biology of signalling, and mechanisms of human disease
Macrophages, Inflammation and Drug Development
David Greaves
Using knowledge of macrophage cell biology to develop new anti-inflammatory and anti-bacterial drugs
R-Loop Biology in Health and Disease
Natalia Gromak
Studying the role of a unique type of non-canonical RNA/DNA structure in healthy cells and in neurodegenerative diseases.
Regulation of Mitotic Progression and Chromosome Segregation
Ulrike Gruneberg
Elucidating how faithful chromosome segregation during cell division is ensured, and how this goes awry in cancer
RNA Dependent DNA Damage Response and Gene Expression Regulation
Monika Gullerova
Understanding how intronic gene silencing is de-regulated in cancer cells and how synthetic tsRNA can be used therapeutically