Structure and Function of Cancer Genes
Identifying and validating functional genomic co-dependencies to improve precision of cancer treatment.
Unpicking host-parasite interactions in molecular detail. Matt Higgins has a joint appointment between the Biochemistry Department, the Kavli Institute and the Dunn School. His group is based in the Dorothy Crowfoot Hodgkin Building.
Molecular Mechanisms of Bacterial Membrane Biogenesis
Using a combination of structural biology, biochemistry and bacterial genetics to study Gram-negative bacterial membrane transport systems
Macrophage Modulation During Viral Infection and Neuroinflammation
Dissecting both physiological and pathological macrophage pathways in infectious and non-infectious disease
Assembly and Regulation of Macromolecular Ciliary Dynein Motors
Girish Ram Mali
Investigating how cells assemble axonemal dyneins, in particular the role of DNAAFs in this process
The Transcriptional Cyclin-Dependent Kinases and Control of Gene Expression
Understanding the mechanisms underlying the connection between transcription and RNA processing
Cell Cycle and Gene Expression in Cancer
Studying the role of cyclin-dependent protein kinases (CDKs) in cancer cells and their normal counterparts
RNA Polymerase II Derived Nascent Transcription and Co-transcriptional RNA Processing in Mammalian Genomes
Studying the molecular mechanisms that define the extent of transcription units generated by RNA polymerase II across mammalian genomes