Improved therapy for spinal muscular atrophy
Published in Cell, a collaboration between the groups of Alberto Kornblihtt (Universidad de Buenos Aires, Argentina), Adrian Krainer (Cold Spring Harbor Laboratory, USA) and Nick Proudfoot (Dunn School) reports an improved treatment for spinal muscular atrophy. Spinal muscular atrophy (SMA) is a genetic disease of the central nervous system, causing muscle weakness and wasting. Affecting...
Novel insight into transcriptional functions of RNase H2 furthers our understanding of Aicardi Goutières Syndrome pathology
Published in Nature Communications, work by the Gromak lab uncovers key new functions for RNase H2 during transcription, and provides molecular explanations for the pathology behind Aicardi Goutières Syndrome. Aicardi Goutières Syndrome (AGS) is a severe neuroinflammatory disease caused by mutations in RNase H2 in more than 50% of the cases. RNase H2 is an...
Prestigious BSCB prize for Iona Manley
The Gruneberg lab student was recognised with the BSCB Young Cell Biologist of the Year Prize At the recent BSCB/BSDB joint spring conference at the University of Warwick, Iona Manley, a 4th year PhD student in the Gruneberg lab, won this year’s BSCB Young Cell Biologist of the Year Prize with her poster “A novel...
Susan Lea and Jordan Raff elected Fellows of the Royal Society
Many congratulations to Susan and Jordan for this prestigious honour, recognising their contributions to structural and centrosome biology, respectively.
Andrii Gorelik awarded Wellcome Fellowship and Lincoln College Fellowship
The prestigious fellowships will allow Dr Gorelik to conduct high-impact independent research on the exciting topic of cysteine ADP-ribosylation. Dr Andrii Gorelik of the Ahel group at the Dunn School was awarded a prestigious Sir Henry Wellcome Postdoctoral Fellowship from the Wellcome Trust and The Jones and Anson Junior Research Fellowship from Lincoln College, Oxford....
Jordan Raff receives Excellence in Science Award
Awarded by the Biochemical Society, this honour recognises his leading role in the field of centriole and centrosome biology.
ADP-ribosylation of DNA in vivo revealed for the first time
A study by the Ivan Ahel group reports the existence of ADP-ribosylation of DNA in vivo and its role in the regulation of bacterial growth. This research could have strong implications for the treatment of tuberculosis. ADP-ribosylation is a modification of macromolecules found across all domains of life and regulates a variety of cellular processes...
Dunn School strengthens its research on bacterial pathogenesis
Dr Georgia Isom and Dr Mathew Stracy lead two new research groups in the Dunn School. March marks the beginning of a new phase at the Dunn School with the arrival of two new research groups, led by Dr Georgia Isom and Dr Mathew Stracy. Both Dr Isom and Dr Stracy have secured highly competitive...
Antibiotic-prescribing algorithm reduces the risk of antibiotic resistance emergence in patients
New paper by the Stracy group uses machine learning to predict individual risk and develop personalised treatment strategies Antibiotics have saved countless lives but their widespread use has led to antibiotic resistance which is increasing throughout the world and threatens our ability to treat dangerous bacterial infections. Despite the significant health and economic burden, little...
Ivan Ahel appointed Professor of Chemical Pathology
We are delighted to announce that Dr Ivan Ahel has been appointed to the E.P. Abraham Chair of Chemical Pathology, in association with Lincoln College.
Green Group celebrates High Sheriff Award
The AWARD recognises efforts to embed sustainable environmental practices across the department The Dunn School Green Group were joint winners of the High Sheriff’s Climate Action Heroes Awards, in the business/public sector category. The award was announced at a ceremony at the Oxford Trust’s Wood Centre for Innovation in Headington Quarry, Oxford on Monday 21 February. Dunn School Gr...
Prof Ulrike Gruneberg awarded a Discovery Programme Award by CRUK
These prestigious 5-year grants from Cancer Research UK (CRUK) “provide long-term support for outstanding established scientists in basic or translational research fields” under CRUK’s overarching aim: “to bring forward the day when all cancers are cured”. Prof Gruneberg first established her research group at the University of Liverpool, joining the Dunn school in 2013, and...
Summer Studentship Program
The Sir William Dunn School of Pathology is launching the 2022 Summer Studentship Program. This program is aimed at undergraduate students excited about research in life sciences and looking for a hands-on experience.
Under the white coat is a green heart
The Dunn School’s actions against climate change are recognised with 13 LEAF Awards The status quo that high quality research is energy-intensive and requires high levels of consumption is now being challenged by conscientious Dunn School researchers. Typically, to ensure samples are well preserved and uncontaminated, scientists are trained to dispose of gloves, reagents, and...
Three Dunn School academics recognised with Full Professor title
Many congratulations to Omer Dushek, Fumiko Esashi and Ulrike Gruneberg We are delighted to announce that three Dunn School group leaders were recognised in this year’s University of Oxford Recognition of Distinction exercise. Omer Dushek is now Professor of Molecular Immunology. His group investigates the immunology of T cell receptor signal integration, at the interface...