Molecular Mechanisms of RNA Virus Replication
Ervin Fodor
Elucidating the fundamental mechanisms underlying the replication of RNA viruses such as Influenza, Nipah, and SARS-CoV-2
R-Loop Biology in Health and Disease
Natalia Gromak
Studying the role of a unique type of non-canonical RNA/DNA structure in healthy cells and in neurodegenerative diseases.
RNA Dependent DNA Damage Response and Gene Expression Regulation
Monika Gullerova
Understanding how intronic gene silencing is de-regulated in cancer cells and how synthetic tsRNA can be used therapeutically
Structure and Function of Cancer Genes
Bass Hassan
Identifying and validating functional genomic co-dependencies to improve precision of cancer treatment.
The Transcriptional Cyclin-Dependent Kinases and Control of Gene Expression
Shona Murphy
Shona Murphy has now retired
Cell Cycle and Gene Expression in Cancer
Chris Norbury
Studying the role of cyclin-dependent protein kinases (CDKs) in cancer cells and their normal counterparts
RNA Polymerase II Derived Nascent Transcription and Co-transcriptional RNA Processing in Mammalian Genomes
Nicholas Proudfoot
Studying the molecular mechanisms that define the extent of transcription units generated by RNA polymerase II across mammalian genomes
Bacterial Pathogenesis: Molecular Mechanisms to Prevention
Christoph Tang
Understanding how pathogens colonise specific niches in the body, evade elimination by the immune system, and cause disease
Molecular Pathology of Post-Translational Modification
David Vaux
Studying the molecular mechanisms by which pathological perturbations in the post-translational modifications of proteins can lead to severe human disease