Research groups

There are currently over 30 research groups at the Dunn School, investigating different aspects of the molecular and cellular basis underlying health and disease.
Research area:

Mechanisms of Genome Stability

Dragana Ahel

Uncovering the mechanisms that maintain genome integrity

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DNA Repair Mechanisms and Human Disease

Ivan Ahel

Exploring the pathways underlying genome stability, in particular the role of the post-translational protein modification ADP-ribosylation

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Genome Stability and Evolution

Fumiko Esashi

Investigating the mechanisms that drive changes in the genome during cell growth and dormancy

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Regulation of Mitotic Progression and Chromosome Segregation

Ulrike Gruneberg

Elucidating how faithful chromosome segregation during cell division is ensured, and how this goes awry in cancer

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RNA Dependent DNA Damage Response and Gene Expression Regulation

Monika Gullerova

Understanding how intronic gene silencing is de-regulated in cancer cells and how synthetic tsRNA can be used therapeutically

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Structure and Function of Cancer Genes

Bass Hassan

Identifying and validating functional genomic co-dependencies to improve precision of cancer treatment.

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Germline mutation and Meiotic recombination

Anjali Hinch

Uncovering the mechanisms and impacts of meiotic recombination and de novo mutation.

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Cell Cycle and Gene Expression in Cancer

Chris Norbury

Studying the role of cyclin-dependent protein kinases (CDKs) in cancer cells and their normal counterparts

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Centrioles, Centrosomes and Cilia in Health and Disease

Jordan Raff

Understanding how centrioles assemble and function, using a combination of biochemistry, genetics, live-cell imaging, computational/structural analysis and mathematical modelling

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Molecular Pathology of Post-Translational Modification

David Vaux

Studying the molecular mechanisms by which pathological perturbations in the post-translational modifications of proteins can lead to severe human disease

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