DNA Repair Mechanisms and Human Disease
Ivan Ahel
Exploring the pathways underlying genome stability, in particular the role of the post-translational protein modification ADP-ribosylation
Molecular immunology of T cell surface receptors
Omer Dushek
Understanding how the immune system discriminates between normal and abnormal tissues, and harnessing this knowledge to develop new therapies
Molecular Mechanisms of RNA Virus Replication
Ervin Fodor
Elucidating the fundamental mechanisms underlying the replication of RNA viruses such as Influenza, Nipah, and SARS-CoV-2
Cell Biology of Signalling
Matthew Freeman
Investigating the interface between membrane proteins, the cell biology of signalling, and mechanisms of human disease
Macrophages, Inflammation and Drug Development
David Greaves
Using knowledge of macrophage cell biology to develop new anti-inflammatory and anti-bacterial drugs
Molecular Parasitology
Matt Higgins
Unpicking host-parasite interactions in molecular detail. Matt Higgins has a joint appointment between the Biochemistry Department, the Kavli Institute and the Dunn School. His group is based in the Dorothy Crowfoot Hodgkin Building.
Molecular Mechanisms of Bacterial Membrane Biogenesis
Georgia Isom
Using a combination of structural biology, biochemistry and bacterial genetics to study Gram-negative bacterial membrane transport systems
Macrophage Modulation During Viral Infection and Neuroinflammation
William James
Dissecting both physiological and pathological macrophage pathways in infectious and non-infectious disease
Recognition of Abnormal Cells by Leukocyte Receptors
Anton van der Merwe
Investigating the mechanisms by which leukocytes use cell surface receptors to recognise infected or otherwise abnormal cells
Mechanisms of Virus Biogenesis and Immune Evasion
Sumana Sanyal
Investigating mechanisms of flavivirus biogenesis, using Zika and Dengue as models, and their strategies of evading host immune responses
Lymphocyte function in health and disease
Quentin Sattentau
Interrogating B cell responses to glycans and small molecules, and regulation of the T cell glycocalyx.
Molecular Mucosal Immunology
Emma Slack
Elucidating the mechanisms by which the mucosal immune system can control the abundance and pathogenicity of opportunistic pathogens
Poxvirus Evasion of Innate Immunity
Geoffrey L Smith
Studying the mechanisms by which orthopoxviruses suppress innate immunity
Mechanisms and Prevention of Antibiotic Resistance and Tolerance
Mathew Stracy
Studying how bacteria respond to antibiotics from multiple perspectives; ranging from molecular biology to infection epidemiology
Bacterial Pathogenesis: Molecular Mechanisms to Prevention
Christoph Tang
Understanding how pathogens colonise specific niches in the body, evade elimination by the immune system, and cause disease