Ian Gibbs-Seymour, a postdoc in Ivan Ahel’s group, has been awarded a Marie Curie Fellowship in the latest funding round.
His project titled: ‘Regulation of ADP-ribosylation signalling in the DNA damage response’ hopes to unveil insights into ADP-ribosylation signalling, genome maintenance pathways and disease prevention.
Ian said: “The project will allow me to build on some exciting preliminary data and explore the physiological relevance of how a post-translational modification, called ADP-ribosylation, contributes to the stability of DNA in our cells. Inability to repair and faithfully restore the genetic material upon damage gives rise to a range diseases, including various cancers. We hope that the work described in this proposal will provide novel mechanistic insights into ADP-ribosylation signalling and further our understanding of its role in genome maintenance pathways.”
Visit the Ivan Ahel group pages for further information about the group’s research.