Research Groups

There are currently over 30 research groups at the Dunn School, with leaders drawn from across the world. Their diverse interests, backgrounds and expertise creates a dynamic and stimulating environment. Many groups share common research interests which fosters the vibrant scientific community found at the Dunn School.

Fumiko Esashi

Genome Stability and Cell Cycle

Our research goal is to elucidate how proliferating human cells safeguard their genomic DNA against various stresses coming from the environment (e.g., UV, radiation, chemicals) and from normal processes of cell growth (e.g., metabolic byproducts, DNA replication, transcription).

Paul Fairchild

Exploring the interface between immunology and regenerative medicine

Although the dramatic increase in life expectancy over the past century is arguably one of medicine’s greatest successes, it is also responsible for the rising incidence of chronic and degenerative diseases throughout the developed world. The properties of induced pluripotent stem cells (iPSC) offer an...

Ervin Fodor

Influenza virus replication at the molecular level

Influenza viruses are important human and animal pathogens. They cause widespread clinical and veterinary disease and have a considerable economic impact. Our laboratory focuses on the fundamental molecular mechanisms of influenza virus replication, aiming to understand the molecular determinants of host range and...

Matthew Freeman

Cell biology of intercellular signalling

The main questions we study are what cellular mechanisms regulate signalling between animal cells, and how does that signalling control biological functions like physiology, development and pathology?

Eva Gluenz

Molecular cell biology of Leishmania

We study single-celled parasites called Leishmania, which cause disease in humans and animals in over 88 countries around the world. Leishmaniasis is a neglected disease, associated with poverty and conflict. There is currently no vaccine and an urgent need for better drug treatments.

Leishmania are...

David Greaves

Regulation of inflammatory responses in vivo

Inflammation is the response of vascularised tissues to injury, metabolic disturbance and infection. Acute inflammation typically lasts only a few days while chronic inflammation can last for months or years, and is a defining feature of many important human diseases including rheumatoid arthritis and coronary heart disease...

Natalia Gromak

Molecular mechanisms of neurodegenerative diseases

Our research focuses on understanding the mechanisms governing gene regulation in humans in health and disease conditions. We are investigating the molecular basis of neurodegenerative diseases arising from dysregulation of RNA transcription and processing. We study Friedreich ataxia (FRDA) and Fragile X syndrome (FXS...

Ulrike Gruneberg

Regulation of mitotic progression and chromosome segregation

Cell division is the fundamental basis for growth and development of an organism. Millions of cell divisions have to occur before an organism reaches its final size. Throughout the life span of an organism, blood, skin and intestinal cells have to be constantly replaced by further cell division. High fidelity...

Keith Gull

Morphogenesis and pathogenicity of trypanosome and Leishmania parasites.

Our research focuses on African trypanosomes, particularly the structural and molecular mechanisms of cell proliferation and differentiation, in relation to pathogenesis. We have particular interests in the following: the molecular cytology of the flagellum and its roles in the host-parasite and...

Monika Gullerova

Transcriptional gene silencing and its role in disease.

Our goal is to understand the role of transcriptional gene silencing in gene expression regulation in mammalian cells. Our research focuses on natural occurrence of sense and antisense overlapping transcripts that lead to RNAi activation in normal and cancer cells. To elucidate these research questions, we employ...