Development and stem cells
Development and stem cells
The following groups perform research in this area:
Macrophage modulation during viral infection and neuroinflammation
We are based in the James & Lillian Martin Centre.
The macrophage is a key cell in human health and disease, and we have developed very powerful methods for dissecting both physiological and pathological pathways in both infectious and non-infectious disease. We are currently focusing most on...
Molecular dissection of centrioles, centrosomes and cilia
Centrioles organise the assembly of two important cell organelles: centrosomes and the cilia; our goal is to understand how these organelles function at the molecular level.
Transcriptional regulators of mammalian development
Our research exploits mouse genetics to investigate the key signalling cues and transcriptional regulators governing cell fate decisions in the developing mammalian embryo. In particular, we have been studying the TGF family of secreted growth factors, including the ligand Nodal, and its downstream effector Smad2,...