Publications
Number of citations and h-index (calculated by Google Scholar)
There are 129 references in this bibliography folder.
Cordoba SP, Chaudhuri K, Zhang H, Bridge M, Basat AB, Dustin ML, and van der Merwe PA (2013).
The large ectodomains of CD45 and CD148 regulate their segregation from and Inhibition of ligated T-cell receptor.
Blood, in press.
Mukhopadhyay H, Cordoba SP, Maini P, van der Merwe PA, and Dushek O (2013).
Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity.
PLoS Comput Biol, 9(3):e1003004.
Allard J, Dushek O, Coombs D, and van der Merwe PA (2012).
Mechanical modulation of receptor-ligand interactions at cell-cell interfaces.
Biophys J, 102(6):1265-73.
Dushek O, Goyette J, and van der Merwe PA (2012).
Non-catalytic tyrosine-phosphorylated receptors.
Immunol Rev, 250(1):258-76.
Illingworth J, and van der Merwe PA (2012).
Dissecting T-cell activation with high-resolution live-cell microscopy.
Immunology, 135(3):198-206.
Robert P, Aleksic M, Dushek O, Cerundolo V, Bongrand P, and van der Merwe PA (2012).
Kinetics and Mechanics of Two-Dimensional Interactions between T Cell Receptors and Different Activating Ligands.
Biophys J, 102(2):248-57.
Stewart-Jones G, Simpson P, van der Merwe PA, Easterbrook P, McMichael A, Rowland-Jones S, Jones EY, and Gillespie G (2012).
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Proc Natl Acad Sci U S A, 109(50):E3483-92.
van der Merwe PA, Zhang H, and Cordoba SP (2012).
Why do some T cell receptor cytoplasmic domains associate with the plasma membrane?
Frontiers in Immunology, 3(29).
Burroughs N, Kohler K, Miloserdov V, Dustin M, van der Merwe PA, and Davis D (2011).
Boltzmann Energy-based Image Analysis Demonstrates that Extracellular Domain Size Differences Explain Protein Segregation at Immune Synapses.
PLoS Comput Biol, 7(8):e1002076.
Coombs D, Dushek O, and van der Merwe P (2011).
Review of mathematical models for T cell receptor triggering and antigen discrimination.
In: Mathematical Models and Immune Cell Biology, ed. by C. Molina-Paris and G. Lythe. Springer, chap. X, pp. X.
Davis S, and van der Merwe PA (2011).
Lck and the nature of the T cell receptor trigger.
Trends Immunol, 32(1):1-5.
Dushek O, Aleksic M, Wheeler R, Zhang H, Cordoba SP, Peng YC, Chen JL, Cerundolo V, Dong T, Coombs D, and van der Merwe PA (2011).
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
Sci Signal, 4(176):ra39.
Dushek O, van der Merwe PA, and Shahrezaei V (2011).
Ultrasensitivity in multisite phosphorylation of membrane-anchored proteins.
Biophys J, 100(5):1189-97.
van der Merwe PA, and Cordoba SP (2011).
Late arrival: recruiting coreceptors to the T cell receptor complex.
Immunity, 34(1):1-3.
van der Merwe PA, and Dushek O (2011).
Mechanisms for T cell receptor triggering.
Nat Rev Immunol, 11(1):47-55.
Zhang H, Cordoba SP, Dushek O, and van der Merwe PA (2011).
Basic residues in the T-cell receptor zeta cytoplasmic domain mediate membrane association and modulate signaling.
Proc Natl Acad Sci U S A, 108(48):19323-8.
Aleksic M, Dushek O, Zhang H, Shenderov E, Chen JL, Cerundolo V, Coombs D, and van der Merwe PA (2010).
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
Immunity, 32(2):163-74.
Brzostek J, Chai J, Gebhardt F, Busch D, Zhao R, van der Merwe P, and Gould K (2010).
Ligand dimensions are important in controlling NK-cell responses.
Eur J Immunol, 40(7):2050-2059.
Chen JL, Morgan A, Stewart-Jones G, Shepherd D, Bossi G, Wooldridge L, Hutchinson S, Sewell A, Griffiths G, van der Merwe PA, Jones EY, Galione A, and Cerundolo V (2010).
Ca2+ release from the endoplasmic reticulum of NY-ESO-1-specific T cells is modulated by the affinity of TCR and by the use of the CD8 coreceptor.
J Immunol, 184(4):1829-39.
Fernandes R, Yu C, Evans A, van der Merwe P, and Davis S (2010).
What controls T cell receptor phosphorylation?
Cell, 142(5):668-9.
Kohler K, Xiong S, Brzostek J, Mehrabi M, Eissmann P, Harrison A, Cordoba SP, Oddos S, Miloserdov V, Gould K, Burroughs N, van der Merwe PA, and Davis D (2010).
Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells.
PLoS One, 5(11):e15374.
van der Merwe P, Dunn P, Klenerman D, and Davis S (2010).
Taking T cell beyond the diffraction limit.
Nat Immunol, 11:51-51.
Choudhuri K, Parker M, Milicic A, Cole D, Shaw M, Sewell A, Stewart-Jones G, Dong T, Gould K, and van der Merwe PA (2009).
Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.
J Biol Chem, 284(38):26096-105.
Harkiolaki M, Holmes S, Svendsen P, Gregersen J, Jensen L, McMahon R, Friese M, van Boxel G, Etzensperger R, Tzartos J, Kranc K, Sainsbury S, Harlos K, Mellins E, Palace J, Esiri M, van der Merwe PA, Jones EY, and Fugger L (2009).
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.
Immunity, 30(3):348-57.
Palmowski M, Parker M, Choudhuri K, Chiu C, Callan MF, van der Merwe PA, Cerundolo V, and Gould K (2009).
A single-chain H-2Db molecule presenting an influenza virus nucleoprotein epitope shows enhanced ability at stimulating CD8+ T cell responses in vivo.
J Immunol, 182(8):4565-71.