Prof Keith Gull

Keith Gull's group is part of the Molecular Microbiology department of the Sir William Dunn School of Pathology. The lab works on several aspects of biology from both an evolutionary and health perspective, but the main focus of the work involves the protozoan parasite Trypanosoma brucei - the causative agent of human sleeping sickness. Among the current research interests of the lab are: the trypanosome cytoskeleton, flagellum and cell morphogenesis, the trypanosome genome structure and nuclear architecture, the process of antigenic variation in African trypanosomes and the flagellum/cilium of mammalian cells in health and disease.

Research Details

• The trypanosome cytoskeleton, flagellum and cell morphogenesis
• The genome of African trypanosomes
• Nuclear architecture and antigenic variation in African trypanosomes
• Pol I Transcription of antigen genes
• The flagellum/cilium of mammalian cells in health and disease
• Parasite: macrophage interactions