Nicholas Proudfoot
Professor of Molecular Biology
Interconnecting transcription and RNA processing in eukaryotes.
| Web | Personal Website |
|---|---|
| nicholas.proudfoot@path.ox.ac.uk | |
| Contact address | Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE |
| Department | Sir William Dunn School of Pathology |
Prof Nick Proudfoot
Regulation of eukaryotic gene expression relies on the interplay between gene structure, transcription and pre-mRNA processing (splicing and polyadenylation). We are investigating this process using genetic and molecular biology technologies in both yeast and mammalian cell lines.
Research Details
- Mechanism and function of transcriptional termination by RNA polymerase II
- Interconnections between mRNA processing and transcription
- Role of polyadenylation in the regulation of gene expression
